Total sulfur amino acid requirement of healthy school-age children as determined by indicator amino acid oxidation technique

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Lysine requirement of healthy, school-aged Indian children determined by the indicator amino acid oxidation technique.

We recently reported the lysine requirement of school-aged children living in Canada consuming a mixed diet to be 35 mg.kg(-1).d(-1). Because the majority of children in the world live on cereal-based diets in developing countries, we measured the daily lysine requirement in healthy children living in India and consuming a mostly cereal-based diet. Our objective in this study was to determine t...

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Lysine requirement of healthy school-age children determined by the indicator amino acid oxidation method.

BACKGROUND The current Dietary Reference Intake (DRI) recommendations for lysine requirements in children are based on a factorial estimate. OBJECTIVE The objective of the current study was to determine the lysine requirement in healthy school-age children by measuring the oxidation of l-[1-(13)C]phenylalanine to (13)CO(2) (F(13)CO(2)) in response to graded intakes of lysine. DESIGN Five he...

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Phenylalanine requirement in children with classical PKU determined by indicator amino acid oxidation.

Dietary restriction of phenylalanine is the main treatment for phenylketonuria (PKU), and current estimates of requirements are based on plasma phenylalanine concentration and growth. The present study aimed to determine more precisely the phenylalanine requirements in patients with the disease by use of indicator amino acid oxidation, with L-[1-13C]lysine as the indicator. Breath 13CO2 product...

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Tryptophan requirement of growing swine as determined by the oxidation of an indicator amino acid.

The tryptophan requirement of growing swine was determined using the oxidation of L-[1-14C]-phenylalanine as an indicator of the adequacy of the dietary tryptophan level. Forty crossbred boars (30 to 45 kg) were fed a basal diet containing 16% protein supplied by corn and gelatin. A series of experimental diets containing .05, .08, .10, .15, .20 and .25% L-tryptophan were prepared. The diets we...

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Tyrosine requirements in children with classical PKU determined by indicator amino acid oxidation.

Tyrosine (Tyr) is an essential amino acid in phenylketonuria (PKU) because of the limited hydroxylation of phenylalanine (Phe) to Tyr. The recommended intakes for Tyr in PKU are at least five times the recommended phenylalanine intakes. This suggests that Phe and Tyr contribute approximately 20 and 80%, respectively, of the aromatic amino acid (AAA) requirement (REQ). In animals and normal huma...

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 2006

ISSN: 0002-9165,1938-3207

DOI: 10.1093/ajcn.83.3.619